Role of Alpha Lipoic Acid on Metabolic Hepatosteatosis: An Experimental, Biochemical, and Microscopic Study
نویسندگان
چکیده
منابع مشابه
Effects of alpha lipoic acid on intra-abdominal adhesion: an experimental study in a rat model.
BACKGROUND This study was performed to determine the effect of alpha lipoic acid, a powerful antioxidant, on intra-abdominal adhesion formation. METHODS Twenty-four female Wistar Albino rats weighing 250-300 g were used in this study conducted on three groups consisting of the alpha lipoic acid group (Group I, n=8), control group (Group II, n=8), and sham group (Group III, n=8). After perform...
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INTRODUCTION We investigated the role of oxidative stress in the pathogenesis of reexpansion pulmonary edema (RPE) and effect of alpha-lipoic acid (ALA) in the prevention of RPE. MATERIAL AND METHODS There were 4 groups consisting of 10 rats in each group; control group (CG), α-lipoic acid group (ALAG), reexpansion pulmonary edema group (RPEG), reexpansion pulmonary edema plus α-lipoic acid g...
متن کاملAlpha-Lipoic Acid
OBJECTIVE: To evaluate the efficacy and safety of oral treatment with the antioxidant alpha-lipoic acid (ALA) in NIDDM patients with cardiac autonomic neuropathy (CAN), assessed by heart rate variability (HRV). RESEARCH DESIGN AND METHODS: In a randomized, double-blind placebo-controlled multicenter trial (Deutsche Kardiale Autonome Neuropathie [DEKAN] Study), NIDDM patients with reduced HRV we...
متن کاملAlpha Lipoic Acid
Alpha lipoic acid, or just lipoic acid (LA), is a unique and potent antioxidant. It can deliver antioxidant activity in both fatand water-soluble mediums, and it is capable of having an antioxidant effect in both its oxidized (LA) and reduced (DHLA [dihydrolipoic acid]) forms (Goraca et al., 2011). This effectively allows LA to deliver its antioxidant effect to any cell or tissue type, as well ...
متن کاملAlpha-lipoic Acid Monograph
Introduction Alpha-lipoic acid (ALA – also known as thioctic acid) was discovered in 1951 as a molecule that assists in acyl-group transfer and as a coenzyme in the Krebs cycle. In the 1980s, the scientific community realized alpha-lipoic acid is a powerful antioxidant. Several qualities distinguish alpha-lipoic acid from other antioxidants: ALA can be synthesized by animals and humans;1 it neu...
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ژورنال
عنوان ژورنال: The Egyptian Journal of Hospital Medicine
سال: 2015
ISSN: 2090-7125
DOI: 10.21608/ejhm.2018.14876